The antidepressant sertraline (Zoloft) may increase the volume of a region of the brain in depressed people — yet shrink other areas in those who aren’t depressed.
Does sertraline change your brain?
The study — conducted in nonhuman primates with brain structures and functions similar to those of humans — found that the antidepressant sertraline, a selective serotonin reuptake inhibitor (SSRI) marketed as Zoloft, significantly increased the volume of one brain region in depressed subjects but decreased the …
Do antidepressants permanently change your brain?
“The fact that antidepressant withdrawal can be so prolonged suggests that the drug has changed the brain and that those changes are taking a very long time to return to normal and it may be the case that sometimes they don’t go back to normal.”
Does Zoloft change your personality?
Medication can definitely change people’s personalities, and change them quite substantially. Paxil is rarely prescribed now, because of concerns about side effects and withdrawal, says Tang, but other SSRIs (such as Prozac and Zoloft) are likely to have the same effect on personality.
What are the long term side effects of Zoloft?
To date, there are no known problems associated with long term use of sertraline. It is a safe and effective medication when used as directed.
Do antidepressants shorten your life?
The analysis found that in the general population, those taking antidepressants had a 33 percent higher risk of dying prematurely than people who were not taking the drugs. Additionally, antidepressant users were 14 percent more likely to have an adverse cardiovascular event, such as a stroke or a heart attack.
Can I take Zoloft for the rest of my life?
How Long Can You Stay on Sertraline? Clinical trials of sertraline show that it’s safe to use for the long-term, with many cases of people using sertraline for years at a time. When used as a treatment for depression, doctors typically recommend using sertraline for up to one year after your depression symptoms end.
What is the safest antidepressant?
The results showed the most acceptable antidepressants were agomelatine, citalopram, escitalopram, fluoxetine, sertraline, and vortioxetine; least acceptable (ones with the highest dropout rates) were amitriptyline, clomipramine, duloxetine, fluvoxamine, reboxetine, trazodone, and venlafaxine.
What happens if you take Zoloft and you’re not depressed?
There is new reason to be cautious about using popular antidepressants in people who are not really depressed. For the first time, research has shown that a widely used antidepressant may cause subtle changes in brain structure and function when taken by those who are not depressed. The drug is sertraline.
Do antidepressants affect memory?
Tranquilizers, antidepressants, some blood pressure drugs, and other medications can affect memory, usually by causing sedation or confusion. That can make it difficult to pay close attention to new things. Talk to your doctor or pharmacist if you suspect that a new medication is taking the edge off your memory.
Can you drink alcohol on Zoloft?
Should I drink when taking Zoloft? Avoid alcohol completely while you take Zoloft. Even a single drink can interact with your medication and cause unwanted side effects. The combination of alcohol and Zoloft can cause side effects, and drinking alcohol can make your depression worse.
How does zoloft make you feel?
People who take Zoloft often report improvements in mood, appetite, sleep quality, energy level, and interest in daily life. Many say that they feel less afraid or anxious and have fewer panic attacks.
What can zoloft do to you?
This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks.
Is Zoloft linked to dementia?
With the exception of paroxetine, the long-term use of most antidepressants does not increase dementia risk, suggests a study published in the Journal of the American Geriatrics Society.
Is Zoloft bad for your liver?
Hepatotoxicity. Liver test abnormalities have been reported to occur in up to 1% of patients on sertraline, but elevations are usually modest and infrequently require dose modification or discontinuation.
How long can you be on Zoloft?
How long will I take it for? Once you’re feeling better it’s likely that you’ll continue to take sertraline for several more months. Most doctors recommend that you take antidepressants for 6 months to a year after you no longer feel depressed. Stopping before that time can make depression come back.