Do not stop trazodone suddenly as withdrawal symptoms may occur. Slow dosage reduction over weeks to months is recommended. Families and caregivers should monitor patients for worsening of depression or suicidal thoughts, particularly during the first few months of therapy, and communicate concerns with the prescriber.
What are the side effects if you stop taking Trazodone?
Trazodone can cause severely uncomfortable withdrawal symptoms.
Some common symptoms of Trazodone withdrawal include:
- Muscle pain.
- Stomach aches.
Can Trazodone be stopped abruptly?
Continue to take trazodone even if you feel well. Do not stop taking trazodone without talking to your doctor. If you suddenly stop taking trazodone, you may experience withdrawal symptoms such as anxiety, agitation, or difficulty falling asleep or staying asleep. Your doctor will probably decrease your dose gradually.
How long does it take for Trazodone to get out of your system?
Trazodone has a half-life between five and 9 hours. This means it will take your body (on average) around seven hours to eliminate half of the drug. In a healthy adult, a single dosage of Trazodone can remain in the body for one to three days.
Do you need to taper off Trazodone?
Nefazodone No recommendations, as reports of withdrawal are rare. Trazodone Reduce gradually over a minimum of 4 weeks. Vilazodone No specific recommendations Tricyclic antidepressant class Reduce gradually over a minimum of 4 weeks. Bupropion Reduce gradually over 1 week, although withdrawal symptoms |are uncommon.
What are the long term side effects of trazodone?
What Are Side Effects Associated with Using Trazodone?
- blurred vision.
- dry mouth.
- headache or mild headache.
Does Trazodone affect memory?
Trazodone produced small but significant impairments of short-term memory, verbal learning, equilibrium, and arm muscle endurance across time points.
Does Trazodone lose its effectiveness for sleep?
Because there’s so little supporting evidence, treatment guidelines by AASM don’t recommend trazodone for the treatment of chronic insomnia. Still, trazodone may improve insomnia symptoms initially, as found in one small study, but this effect could fade after a few weeks. Insomnia with depression.
Can Trazodone be cut in half?
The tablet can be swallowed whole or given as a half tablet by breaking the tablet along the score line. Do not break the tablet unless your doctor tells you to. Do not crush or chew the tablet.
Is trazodone safe long term?
When used to treat depression, it is usually recommended that you remain on the therapeutic dose of an antidepressant medication for 6-12 months after depression has responded to treatment. As far as is known, trazodone is safe for long-term use.
What should you not take with Trazodone?
Drugs you should not use with trazodone
Examples of these drugs include: Monoamine oxidase inhibitors (MAOIs), such as isocarboxazid, phenelzine, tranylcypromine, or selegiline. You shouldn’t take trazodone with MAOIs or within 14 days of taking them. Taking these drugs together raises your risk for serotonin syndrome.
How long will trazodone make you sleep?
Patients who take the drug for a sleep disorder can experience the sedative effects within 30 minutes, depending on the type used. Patients who take the drug as an antidepressant may not notice symptom relief for one to two weeks, and it may take up to four weeks to experience the full benefits.
Does Trazodone cause weight gain?
Trazodone can make you feel more or less hungry than usual, so you may lose or gain weight when you start taking it. If you start to have problems with your weight while taking trazodone, talk to your doctor or pharmacist.
Can trazodone cause dementia?
In this study of UK population-based electronic health records, we found no association between trazodone use and a reduced risk of dementia compared with other antidepressants. These results suggest that the clinical use of trazodone is not associated with a reduced risk of dementia.
Is trazodone like Xanax?
Xanax is similar to trazodone in that it may cause side effects such as feeling tired and drowsy. When this occurs during the day, it can affect your day-to-day activities. However, unlike trazodone, Xanax and other benzodiazepine drugs can be addictive, even if you’ve been using them as directed.
What is the half life of trazodone?
Trazodone has biphasic elimination, with a redistribution half-life of about one hour and an elimination half-life of 10-12 hours. Trazodone is nearly completely metabolized hepatically by hydroxylation and oxidation to metabolites that are probably inactive.