Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.
Does Cymbalta work right away?
Duloxetine normally takes 2 to 4 weeks to work. It may take longer if you’re taking it for nerve pain. Common side effects include feeling sick, a dry mouth, headache, constipation and feeling sleepy. These side effects are usually mild and go away after a couple of weeks.
Is Duloxetine a strong antidepressant?
In company-sponsored research, duloxetine has been as effective as other antidepressants. It is promoted as having a more balanced and stronger effect on serotonin and norepinephrine transmission than its dual-action predecessors, but this advantage has not yet been proved.
How well does Cymbalta work for depression?
Cymbalta has an average rating of 6.3 out of 10 from a total of 528 ratings for the treatment of Depression. 52% of those users who reviewed Cymbalta reported a positive effect, while 29% reported a negative effect.
Can Cymbalta make you more depressed?
Duloxetine may cause some teenagers and young adults to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed.
Will Cymbalta give me energy?
Taking Cymbalta can improve mood, sleep, appetite and energy levels while also decreasing nervousness. For medical conditions such as chronic back pain and fibromyalgia, it works to relieve pain.
Is Cymbalta 30 mg effective for anxiety?
User Reviews for Cymbalta to treat Generalized Anxiety Disorder. Cymbalta has an average rating of 6.5 out of 10 from a total of 101 ratings for the treatment of Generalized Anxiety Disorder. 59% of those users who reviewed Cymbalta reported a positive effect, while 28% reported a negative effect.
How do you know Duloxetine is working?
How Long Does It Take For Duloxetine To Work? Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working.
Is it better to take duloxetine in the morning or at night?
It is best to take duloxetine at the same time each day. Most people take it in the morning. If you find that you feel drowsy after taking it in the morning, try taking it in the evening.
Does Duloxetine make you gain weight?
Most related research suggests that Cymbalta can affect a person’s weight, but only modestly. When people do experience weight changes, they are more likely to lose weight, rather than gain it, while taking Cymbalta short-term.
Does Cymbalta make you feel like a zombie?
Antidepressants won’t make you a “zombie.”
Cox says. But sometimes people actually feel dazed or foggy because of high levels of anxiety or depression, she says, and taking medication helps them feel more clearheaded.
Can I drink coffee with Cymbalta?
If you drink a lot of coffee, cola drinks or other caffeine drinks when taking duloxetine, it can put you at a higher risk of getting serotonin syndrome. The symptoms are any combination of the following: high fever.
Does Cymbalta make you feel good?
How long does it take for Cymbalta (duloxetine) to take effect? Within one to two weeks, you can feel your sleep, energy or appetite improving. The full effects of Cymbalta (duloxetine) on improving your mood can take up to 12 weeks.
Is 90 mg of duloxetine a lot?
Mean increase in heart rate was 5.9 bpm, while patients exhibited a mean weight increase of 3.1 kg over 2 years of treatment. Results from this study suggest that rapid dose escalation of duloxetine (60 mg/day –> 90 mg/day –> 120 mg/day) is safe and tolerable.
Can I start Cymbalta at 60 mg?
Adults—At first, 60 milligrams (mg) once a day. Some patients may start at 30 mg once a day for 1 week before increasing the dose to 60 mg once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 120 mg per day.
What does Cymbalta do to the brain?
Cymbalta inhibits the reuptake of serotonin and norepinephrine in the central nervous system. It also increases dopamine by acting on dopamine reuptake pumps, thus increasing the diffusion of dopamine in the brain.