Considering the limited data available on long-term, selective serotonin reuptake inhibitor management, we report for the first time on two cases of late-onset adverse effects occurring 6 and 10 years after chronic-fluoxetine treatment in which patients experienced symptoms of restlessness, tension, agitation, and …
Is fluoxetine safe to take long term?
For most people, fluoxetine is safe to take for a long time. A few people may get sexual side effects, such as problems getting an erection or a lower sex drive. In some cases these can continue even after stopping the medicine. Speak to your doctor if you are worried.
How long can you stay on fluoxetine?
How long will I need to take fluoxetine? Most people take fluoxetine for at least six to 12 months after they start to feel better. If you have suffered from depression in the past, you should keep taking this medication for at least two years after you start to feel better.
Can Prozac cause memory problems?
Postmarketing studies and isolated case reports, however, suggest that fluoxetine may harm memory in some patients. Some selective serotonin-reuptake inhibitors (SSRIs) appear to cause memory loss more frequently than others.
Is it bad to be on antidepressants for a long time?
Long-term—even indefinite—use of antidepressants may be the best treatment for someone with multiple past episodes of depression, especially if they have a history of suicide attempts or have residual symptoms, like sleep problems, says Dr. Potash.
Why is Prozac bad?
The “if depressed, then Prozac” model puts millions of people needlessly at risk of serious side effects. The most dangerous of these is an “overstimulation reaction” that has been linked to compulsive thoughts of suicide and violence.
Is Prozac bad for your liver?
Fluoxetine has been noted to cause asymptomatic liver enzyme elevations in about 0.5% of patients. The safety of fluoxetine-an update. Recently, fluoxetine-associated chronic hepatitis was reported.
Can Prozac cause weight gain?
Prozac is not alone in causing this potential dreaded side effect; many antidepressants can potentially lead to weight gain, particularly with long-term use. 1In fact, Prozac is actually considered one of the weight-neutral antidepressants, meaning it doesn’t typically cause weight gain.
What happens if you stop taking fluoxetine?
Stopping fluoxetine abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, dizziness, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin). Depression is also a part of bipolar illness.
Is Prozac a happy pill?
“Happy pills” — in particular the anxiolytic drugs Miltown and Valium and the antidepressant Prozac — have been spectacularly successful “products” over the last 5 decades, largely because they have widespread off label use. Miltown, launched in the 1950s, was the first “blockbuster” psychotropic drug in the US.
Does Prozac lead to dementia?
According to the study, popular Prozac-like pills known as SSRIs — selective serotonin reuptake inhibitors — and other antidepressants are associated with a twofold increase in the odds of developing some form of dementia, including Alzheimer’s.
What Prozac does to the brain?
As an SSRI, Prozac works by preventing the brain from reabsorbing naturally occurring serotonin. Serotonin is involved in mood regulation. In this way, Prozac helps the brain to maintain enough serotonin so that you have a feeling of well-being, resulting from improved communication between brain cells.
Does fluoxetine damage the brain?
In conclusion, our data reveal that chronic fluoxetine exposure causes on the long-term changes in expression of genes involved in myelination, a process that shapes brain connectivity and contributes to symptoms of psychiatric disorders.
Do Antidepressants change your brain permanently?
Selective serotonin reuptake inhibitors (SSRI) such as Prozac are regularly used to treat severe anxiety and depression. They work by immediately increasing the amount of serotonin in the brain and by causing long term changes in brain function.
How long should you stay on antidepressants?
Clinicians generally recommend staying on the medication for six to nine months before considering going off antidepressants. If you’ve had three or more recurrences of depression, make that at least two years.
What is the safest antidepressant?
The results showed the most acceptable antidepressants were agomelatine, citalopram, escitalopram, fluoxetine, sertraline, and vortioxetine; least acceptable (ones with the highest dropout rates) were amitriptyline, clomipramine, duloxetine, fluvoxamine, reboxetine, trazodone, and venlafaxine.